Prognostic role and clinicopathological features of SMAD4 gene mutation in colorectal cancer: a systematic review and meta-analysis

Prognostic role and clinicopathological features of SMAD4 gene mutation in colorectal cancer: a systematic review and meta-analysis

Abstract Background Approximately 5.0–24.2% of colorectal cancers (CRCs) have inactivating mutations in SMAD4, making it one of the frequently mutated genes in CRC. We thus carried out a comprehensive system review and meta-analysis investigating the prognostic significance and clinicopathological f...

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Bibliographic Details
Main Authors: Tian Fang, Tingting Liang, Yizhuo Wang, Haitao Wu, Shuhan Liu, Linying Xie, Jiaying Liang, Chang Wang, Yehui Tan
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Gastroenterology
Subjects:
SMAD4
Gene mutation
Colorectal cancer
Prognosis
Meta-analysis
Online Access:https://doi.org/10.1186/s12876-021-01864-9

Internet

https://doi.org/10.1186/s12876-021-01864-9

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