Reduced NOV/CCN3 Expression Limits Inflammation and Interstitial Renal Fibrosis after Obstructive Nephropathy in Mice.

Reduced NOV/CCN3 Expression Limits Inflammation and Interstitial Renal Fibrosis after Obstructive Nephropathy in Mice.

The main hallmark of chronic kidney disease (CKD) is excessive inflammation leading to interstitial tissue fibrosis. It has been recently reported that NOV/CCN3 could be involved in kidney damage but its role in the progression of nephropathies is poorly known. NOV/CCN3 is a secreted multifunctional...

Full description

Bibliographic Details
Main Authors: Pierre-Olivier Marchal, Panagiotis Kavvadas, Ahmed Abed, Chantal Kazazian, Florence Authier, Haruhiko Koseki, Shuichi Hiraoka, Jean-Jacques Boffa, Cécile Martinerie, Christos E Chadjichristos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4569074?pdf=render

Internet

http://europepmc.org/articles/PMC4569074?pdf=render

Similar Items