Estimated intracranial volume from FreeSurfer is biased by total brain volume

Abstract Background Estimated intracranial volume (eTIV) from FreeSurfer is not segmentation-based but calculated from the alignment of the input magnetic resonance (MR) images to the MNI305 brain atlas, an approach that could lead to a bias by total brain volume. If eTIV is unbiased, variance beyon...

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Bibliographic Details
Main Authors: Niklas Klasson, Erik Olsson, Carl Eckerström, Helge Malmgren, Anders Wallin
Format: Article
Language:English
Published: SpringerOpen 2018-09-01
Series:European Radiology Experimental
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41747-018-0055-4