Addition of Partial Envelope Domain II into Envelope Domain III of Dengue Virus Antigen Potentiates the Induction of Virus-Neutralizing Antibodies and Induces Protective Immunity

Dengue virus (DENV) comprises four serotypes in the family <i>Flaviviridae</i> and is a causative agent of dengue-related diseases, including dengue fever. Dengue fever is generally a self-limited febrile illness. However, secondary infection of patients with a suboptimal antibody (Ab) r...

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Bibliographic Details
Main Authors: Jisang Park, Hyun-Young Lee, Ly Tuan Khai, Nguyen Thi Thu Thuy, Le Quynh Mai, Yong-Suk Jang
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/1/88