Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease.

Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease.

To replicate the associations of leukocyte telomere length (LTL) with variants at four loci and to investigate their associations with coronary heart disease (CHD) and type II diabetes (T2D), in order to examine possible causal effects of telomere maintenance machinery on disease aetiology.Four SNPs...

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Bibliographic Details
Main Authors: Cécilia G Maubaret, Klelia D Salpea, Casey E Romanoski, Lasse Folkersen, Jackie A Cooper, Coralea Stephanou, Ka Wah Li, Jutta Palmen, Anders Hamsten, Andrew Neil, Jeffrey W Stephens, Aldons J Lusis, Per Eriksson, Philippa J Talmud, Steve E Humphries, Simon Broome Research Group, EARSII consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3861448?pdf=render

Internet

http://europepmc.org/articles/PMC3861448?pdf=render

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