Heterotachy in mammalian promoter evolution.

We have surveyed the evolutionary trends of mammalian promoters and upstream sequences, utilising large sets of experimentally supported transcription start sites (TSSs). With 30,969 well-defined TSSs from mouse and 26,341 from human, there are sufficient numbers to draw statistically meaningful con...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-04-01
Series:PLoS Genetics
Online Access:http://dx.doi.org/10.1371/journal.pgen.0020030