Cloning, Expression and Purification of the Recombinant HIV-1 Tat-Nef Fusion Protein in Prokaryotic Expression System

Abstract Background: Nef is one of the HIV-1 critical proteins, because it is essential for viral replication and AIDS disease progression and induction of immune response against it can partially inhibit viral infection. Moreover, a domain of the HIV-1 Trans-Activator of Transcription (Tat, 48-60...

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Bibliographic Details
Main Authors: Somayeh Kadkhodayan, Shiva Irani, Seyed Mehdi Sadat, Fatemeh Fotouhi, Azam Bolhassani
Format: Article
Language:fas
Published: Arak Medical University 2016-07-01
Series:Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk
Subjects:
Nef
Tat
Online Access:http://amuj.arakmu.ac.ir/article-1-4231-en.pdf