Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells

Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells

Combination radiation and chemotherapy are commonly used to treat locoregionally advanced head and neck squamous cell carcinoma (HNSCC). Aggressive dosing of these therapies is significantly hampered by side effects due to normal tissue toxicity. Selenium represents an adjuvant that selectively sens...

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Bibliographic Details
Main Authors: John T. Lafin, Ehab H. Sarsour, Amanda L. Kalen, Brett A. Wagner, Garry R. Buettner, Prabhat C. Goswami
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
head and neck cancer
selenium
methylseleninic acid
radiation
lipid peroxidation
glutathione
tocopherol
Online Access:http://www.mdpi.com/1422-0067/20/1/225

Internet

http://www.mdpi.com/1422-0067/20/1/225

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