Hepatic Surgical Stress Promotes Systemic Immunothrombosis That Results in Distant Organ Injury

Hepatic Surgical Stress Promotes Systemic Immunothrombosis That Results in Distant Organ Injury

Innate immunity can initiate platelet activation during the development of thrombosis through a process, termed immunothrombosis. Neutrophils form neutrophil extracellular traps (NETs) that have been shown to interact directly with platelets and play pro-coagulant roles in a variety of infectious an...

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Bibliographic Details
Main Authors: Hongji Zhang, Julie Goswami, Patrick Varley, Dirk J. van der Windt, Jinghua Ren, Patricia Loughran, Hamza Yazdani, Matthew D. Neal, Richard L. Simmons, Jinxiang Zhang, Allan Tsung, Hai Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
neutrophil extracellular traps
immunothrombosis
platelets
liver sterile inflammation
surgical stress
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00987/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00987/full

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