P38 mitogen-activated protein kinase inhibition attenuates mechanical stress induced lung injury via up-regulating AQP5 expression in rats

P38 mitogen-activated protein kinase inhibition attenuates mechanical stress induced lung injury via up-regulating AQP5 expression in rats

The aim of this study was to detect aquaporin-5 (AQP5) expression and evaluate the role of the p38-MAPK signalling pathway in mechanical ventilation-associated lung injury. Rats were randomly divided into 5 groups. In Group C, only trachea were cut to retain spontaneous breathing; in Group S and Gro...

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Bibliographic Details
Main Authors: Yang Liu, Yuelan Wang, Xiumei Song, Ling Dong, Wei Wang, Hongchao Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
lung injury
aquaporin-5
p38 mapk
mechanical ventilation
Online Access:http://dx.doi.org/10.1080/13102818.2019.1590159

Internet

http://dx.doi.org/10.1080/13102818.2019.1590159

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