Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases

Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases

Fibroblasts are found to be heterogeneous in multiple fibrotic diseases, but fibroblast heterogeneity in fibrotic skin diseases is not well characterized. Here the authors employ scRNA-seq to explore fibroblast heterogeneity in keloid, a paradigm of fibrotic skin diseases.

Bibliographic Details
Main Authors: Cheng-Cheng Deng, Yong-Fei Hu, Ding-Heng Zhu, Qing Cheng, Jing-Jing Gu, Qing-Lan Feng, Li-Xue Zhang, Ying-Ping Xu, Dong Wang, Zhili Rong, Bin Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24110-y

Internet

https://doi.org/10.1038/s41467-021-24110-y

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