Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR.
Activation of the latent kinase PKR is a potent innate defense reaction of vertebrate cells towards viral infections, which is triggered by recognition of viral double-stranded (ds) RNA and results in a translational shutdown. A major gap in our understanding of PKR's antiviral properties conce...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-06-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC2688073?pdf=render |