MDM2 negatively regulates the human telomerase RNA gene promoter

<p>Abstract</p> <p>Background</p> <p>We have previously demonstrated that NF-Y and Sp1 interact with the human telomerase RNA (hTR) promoter and play a central role in its regulation. We have also shown that pRB activates the hTR promoter, but the mechanism of pRb direc...

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Bibliographic Details
Main Authors: Keith W Nicol, Jackson Katrina, Bilsland Alan, Zhao Jiangqin
Format: Article
Language:English
Published: BMC 2005-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/6