Host Transcriptional Response to Persistent Infection with a Live-Attenuated Porcine Reproductive and Respiratory Syndrome Virus Strain

Host Transcriptional Response to Persistent Infection with a Live-Attenuated Porcine Reproductive and Respiratory Syndrome Virus Strain

Both virulent and live-attenuated porcine reproductive and respiratory syndrome virus (PRRSV) strains can establish persistent infection in lymphoid tissues of pigs. To investigate the mechanisms of PRRSV persistence, we performed a transcriptional analysis of inguinal lymphoid tissue collected from...

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Bibliographic Details
Main Authors: Jayeshbhai Chaudhari, Chia-Sin Liew, Aspen M. Workman, Jean-Jack M. Riethoven, David Steffen, Sarah Sillman, Hiep L. X. Vu
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
PRRSV
persistent infection
RNA-sequencing
transcriptome
apoptosis
T-cell exhaustion
Online Access:https://www.mdpi.com/1999-4915/12/8/817

Internet

https://www.mdpi.com/1999-4915/12/8/817

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