siRNA suppression of hTERT using activatable cell-penetrating peptides in hepatoma cells

Activatable cell-penetrating peptides (aCPPs) allow non-viral, low cytotoxic and selective delivery of compounds into target cells for cancer therapy. In tumour cells, up-regulation of human telomerase reverse transcriptase (hTERT) frequently occurs and is being considered as a target in cancer diag...

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Bibliographic Details
Main Authors: Hua Li, Jiwen He, Huimin Yi, Guoan Xiang, Kaiyun Chen, Binsheng Fu, Yang Yang, Guihua Chen
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2015-03-01
Series:Bioscience Reports
Subjects:
Online Access:http://www.bioscirep.org/bsr/035/e181/bsr035e181.htm