Single-particle cryo-EM of the ryanodine receptor channel

Ryanodine receptors (RyRs) are tetrameric ligand-gated Ca2+ release channels that are responsible for the increase of cytosolic Ca2+ concentration leading to muscle contraction. Our current understanding of RyR channel gating and regulation is greatly limited due to the lack of a high-resolution str...

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Bibliographic Details
Main Authors: Mariah R. Baker, Guizhen Fan, Irina I. Serysheva
Format: Article
Language:English
Published: PAGEPress Publications 2015-01-01
Series:European Journal of Translational Myology
Subjects:
Online Access:http://pagepressjournals.org/index.php/bam/article/view/4803