Single-particle cryo-EM of the ryanodine receptor channel
Ryanodine receptors (RyRs) are tetrameric ligand-gated Ca2+ release channels that are responsible for the increase of cytosolic Ca2+ concentration leading to muscle contraction. Our current understanding of RyR channel gating and regulation is greatly limited due to the lack of a high-resolution str...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2015-01-01
|
Series: | European Journal of Translational Myology |
Subjects: | |
Online Access: | http://pagepressjournals.org/index.php/bam/article/view/4803 |