Dysregulated Mitochondrial Genes and Networks with Drug Targets in Postmortem Brain of Patients with Posttraumatic Stress Disorder (PTSD) Revealed by Human Mitochondria-Focused cDNA Microarrays

<p>Posttraumatic stress disorder (PTSD) is associated with decreased activity in the dorsolateral prefrontal cortex (DLPFC), the brain region that regulates working memory and preparation and selection of fear responses. We investigated gene expression profiles in DLPFC Brodmann area (BA) 46 o...

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Bibliographic Details
Main Author: Yan A. Su, Jun Wu, Lei Zhang, Qiuyang Zhang, David M. Su, Ping He, Bi-Dar Wang, He Li, Maree J. Webster, Traumatic Stress Brain Study Group, Owen M. Rennert, Robert J. Ursano
Format: Article
Language:English
Published: Ivyspring International Publisher 2008-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v04p0223.htm