Are anticapsular antibodies the primary mechanism of protection against invasive pneumococcal disease?

Antibody to capsular polysaccharide has been the basis of several vaccines that offer protection against invasive disease from Streptococcus pneumoniae. The success of such vaccines has led to the inference that natural protection against invasive pneumococcal disease is largely conferred by anticap...

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Bibliographic Details
Main Authors: Marc Lipsitch, Cynthia G Whitney, Elizabeth Zell, Tarja Kaijalainen, Ron Dagan, Richard Malley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-01-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC545206?pdf=render