Bioguided Isolation of Cyclopenin Analogues as Potential SARS-CoV-2 M<sup>pro</sup> Inhibitors from <i>Penicillium citrinum</i> TDPEF34

Bioguided Isolation of Cyclopenin Analogues as Potential SARS-CoV-2 M<sup>pro</sup> Inhibitors from <i>Penicillium citrinum</i> TDPEF34

SARS-CoV-2 virus mutations might increase its virulence, and thus the severity and duration of the ongoing pandemic. Global drug discovery campaigns have successfully developed several vaccines to reduce the number of infections by the virus. However, finding a small molecule pharmaceutical that is...

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Bibliographic Details
Main Authors: Bathini Thissera, Ahmed M. Sayed, Marwa H. A. Hassan, Sayed F. Abdelwahab, Ngozi Amaeze, Valeria T. Semler, Faizah N. Alenezi, Mohammed Yaseen, Hani A. Alhadrami, Lassaad Belbahri, Mostafa E. Rateb
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
<i>Penicillium citrinum</i>
cyclopenin
SARS-CoV-2
M<sup>pro</sup>
docking
molecular dynamic simulations
Online Access:https://www.mdpi.com/2218-273X/11/9/1366

Internet

https://www.mdpi.com/2218-273X/11/9/1366

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