The Intersection between Oral Microbiota, Host Gene Methylation and Patient Outcomes in Head and Neck Squamous Cell Carcinoma

The Intersection between Oral Microbiota, Host Gene Methylation and Patient Outcomes in Head and Neck Squamous Cell Carcinoma

The role of oral microbiota in head and neck squamous cell carcinoma (HNSCC) is poorly understood. Here we sought to evaluate the association of the bacterial microbiome with host gene methylation and patient outcomes, and to explore its potential as a biomarker for early detection or intervention....

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Bibliographic Details
Main Authors: Zigui Chen, Po Yee Wong, Cherrie W. K. Ng, Linlin Lan, Sherwood Fung, Jing W. Li, Liuyang Cai, Pu Lei, Qianqian Mou, Sunny H. Wong, William K. K. Wu, Ryan J. Li, Katie Meehan, Vivian W. Y. Lui, Chit Chow, Kwok W. Lo, Amy B. W. Chan, Siaw Shi Boon, Eric H. L. Lau, Zenon Yeung, Kwan C. Allen Chan, Eddy W. Y. Wong, Alfred S. L. Cheng, Jun Yu, Paul K. S. Chan, Jason Y. K. Chan
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
HNSCC
microbiome
<i>Fusobacterium</i>
methylation
host-microbiome interaction
Online Access:https://www.mdpi.com/2072-6694/12/11/3425

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https://www.mdpi.com/2072-6694/12/11/3425

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