Integrative Analysis of Human Macrophage Inflammatory Response Related to Mycobacterium tuberculosis Virulence

Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis, kills 1.5 to 1.7 million people every year. Macrophages are Mtb’s main host cells and their inflammatory response is an essential component of the host defense against Mtb. However, Mtb is able to circumvent the macrophages’ de...

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Bibliographic Details
Main Authors: Pauline Bade, Fabrizio Simonetti, Stephanie Sans, Patricia Laboudie, Khadija Kissane, Nicolas Chappat, Sophie Lagrange, Florence Apparailly, Christine Roubert, Isabelle Duroux-Richard
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.668060/full