Activation of an Effective Immune Response after Yellow Fever Vaccination Is Associated with the Genetic Background and Early Response of IFN-γ and CLEC5A

Activation of an Effective Immune Response after Yellow Fever Vaccination Is Associated with the Genetic Background and Early Response of IFN-γ and CLEC5A

The yellow fever vaccine (YF17DD) is highly effective with a single injection conferring protection for at least 10 years. The YF17DD induces polyvalent responses, with a TH1/TH2 CD4<sup>+</sup> profile, robust T CD8<sup>+</sup> responses, and synthesis of interferon-gamma (I...

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Bibliographic Details
Main Authors: Tamiris Azamor, Andréa Marques Vieira da Silva, Juliana Gil Melgaço, Ana Paula dos Santos, Caroline Xavier-Carvalho, Lucia Elena Alvarado-Arnez, Leonardo Ribeiro Batista-Silva, Denise Cristina de Souza Matos, Camilla Bayma, Sotiris Missailidis, Ana Paula Dinis Ano Bom, Milton Ozorio Moraes, Patrícia Cristina da Costa Neves
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
yellow fever vaccine
interferon gamma
CLEC5A
Online Access:https://www.mdpi.com/1999-4915/13/1/96

Internet

https://www.mdpi.com/1999-4915/13/1/96

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