The role of the epithelial Na+ channel (ENaC) in high AVP but low aldosterone states

Due to the abundance of seminal discoveries establishing a strong causal relation between changes in aldosterone signaling, the activity of the epithelial Na+ channel (ENaC) and blood pressure, the role of ENaC in health and disease is understood almost exclusively through the concept that this chan...

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Bibliographic Details
Main Author: James D Stockand
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00304/full