Bone Marrow-Derived Mononuclear Cells Promote Improvement in Glomerular Function in Rats with Early Diabetic Nephropathy

Bone Marrow-Derived Mononuclear Cells Promote Improvement in Glomerular Function in Rats with Early Diabetic Nephropathy

Background/Aims: Diabetic nephropathy is one of the main causes of end-stage renal disease. The present study investigated the effect of mononuclear cell (MC) therapy in rats subjected to diabetic nephropathy. Methods: Male Wistar rats were divided into control (CTRL), diabetic (DM), CTRL+MC and DM+...

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Main Authors: Raquel C. Castiglione, Tatiana Maron-Gutierrez, Carolina M.L. Barbosa, Felipe M. Ornellas, André Luis Barreira, Carolina B.A. diBarros, Andréia Vasconcelos-dos-Santos, Bruno Diaz Paredes, Bernardo M. Pascarelli, Bruno L. Diaz, Bartira Rossi-Bergmann, Christina M. Takiya, Patricia R.M. Rocco, Jackson Souza-Menezes, Marcelo M. Morales
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Bone marrow mononuclear cells
Diabetic nephropathy
Renal function
Arginase I+ macrophages
Cytokines
Online Access:http://www.karger.com/Article/FullText/354473

Internet

http://www.karger.com/Article/FullText/354473

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