Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection

Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection

O'nyong-nyong virus (ONNV) is an arthritogenic alphavirus that caused two large epidemics in 1959 and 1996, affecting millions of people in Africa. More recently, sero-surveillance of healthy blood donors conducted in 2019 revealed high rates of unreported ONNV infection in Uganda. Due to simil...

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Bibliographic Details
Main Authors: Yi-Hao Chan, Teck-Hui Teo, Anthony Torres-Ruesta, Siddesh V. Hartimath, Rhonda Sin-Ling Chee, Shivashankar Khanapur, Fui Fong Yong, Boominathan Ramasamy, Peter Cheng, Ravisankar Rajarethinam, Edward G. Robins, Julian L. Goggi, Fok-Moon Lum, Guillaume Carissimo, Laurent Rénia, Lisa F. P. Ng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
O'nyong-nyong virus
alphavirus
immunopathogenesis
CD4+ T cells
drug repositioning
PET imaging
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00894/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00894/full

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