New perspectives on the computational characterization of the kinetics of binding-unbinding in drug design: implications for novel therapies
The efficiency and the propensity of a drug to be bound to its target protein have been inseparable concepts for decades now. The correlation between the pharmacological activity and the binding affinity has been the first rule to design and optimize a new drug rationally. However, this argument doe...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Permanyer
2016-11-01
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| Series: | Boletín Médico del Hospital Infantil de México |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665114616301447 |