ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration

Stress response JNK signalling is important for cell death-induced regeneration. Here the authors show in adultDrosophilaenterocytes that ATF3 regulates the expression of Raw, a JNK antagonist, to control intestinal regeneration and barrier function in response to infection.

Bibliographic Details
Main Authors: Jun Zhou, Bruce A. Edgar, Michael Boutros
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14289