Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease
One of the defining pathological features of Alzheimer disease (AD) is the intraneuronal accumulation of tau. Tau that forms these accumulations is altered both posttranslationally and conformationally, and there is now significant evidence that soluble forms of these modified tau species are the t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013-09-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00122/full |