Motor network degeneration in amyotrophic lateral sclerosis: a structural and functional connectivity study.

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by motor neuron degeneration. How this disease affects the central motor network is largely unknown. Here, we combined for the first time structural and functional imaging measures on the motor network in pa...

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Bibliographic Details
Main Authors: Esther Verstraete, Martijn P van den Heuvel, Jan H Veldink, Niels Blanken, René C Mandl, Hilleke E Hulshoff Pol, Leonard H van den Berg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2965124?pdf=render