SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes

SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes

The icosahedral capsid structure of simian virus 40 (diameter, 45 nm) consists of 72 pentameric subunits, with each subunit formed by five VP1 molecules. Electron microscopy, immuno-gold labeling, and ζ-potential analysis showed that purified recombinant VP1 pentamers covered polystyrene beads measu...

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Bibliographic Details
Main Authors: Masaaki Kawano, Koji Doi, Hajime Fukuda, Yoshinori Kita, Kensuke Imai, Takamasa Inoue, Teruya Enomoto, Masanori Matsui, Mamoru Hatakeyama, Yuki Yamaguchi, Hiroshi Handa
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Biotechnology Reports
Subjects:
Polyomavirus
Simian virus 40
VP1
VP1 coating
Artificial beads
Drug delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X14000642

Internet

http://www.sciencedirect.com/science/article/pii/S2215017X14000642

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