Caspase-12 silencing attenuates inhibitory effects of cigarette smoke extract on NOD1 signaling and hBDs expression in human oral mucosal epithelial cells.

Caspase-12 silencing attenuates inhibitory effects of cigarette smoke extract on NOD1 signaling and hBDs expression in human oral mucosal epithelial cells.

Cigarette smoke exposure is associated with increased risk of various diseases. Epithelial cells-mediated innate immune responses to infectious pathogens are compromised by cigarette smoke. Although many studies have established that cigarette smoke exposure affects the expression of Toll-liked rece...

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Bibliographic Details
Main Authors: Xiang Wang, Ya-jie Qian, Qian Zhou, Pei Ye, Ning Duan, Xiao-feng Huang, Ya-nan Zhu, Jing-jing Li, Li-ping Hu, Wei-yun Zhang, Xiao-dong Han, Wen-mei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4263745?pdf=render

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http://europepmc.org/articles/PMC4263745?pdf=render

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