Transcriptomic coordination in the human metabolic network reveals links between n-3 fat intake, adipose tissue gene expression and metabolic health.

Transcriptomic coordination in the human metabolic network reveals links between n-3 fat intake, adipose tissue gene expression and metabolic health.

Understanding the molecular link between diet and health is a key goal in nutritional systems biology. As an alternative to pathway analysis, we have developed a joint multivariate and network-based approach to analysis of a dataset of habitual dietary records, adipose tissue transcriptomics and com...

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Bibliographic Details
Main Authors: Melissa J Morine, Audrey C Tierney, Ben van Ommen, Hannelore Daniel, Sinead Toomey, Ingrid M F Gjelstad, Isobel C Gormley, Pablo Pérez-Martinez, Christian A Drevon, Jose López-Miranda, Helen M Roche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3207936?pdf=render

Internet

http://europepmc.org/articles/PMC3207936?pdf=render

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