Arrhythmogenic and antiarrhythmic actions of late sustained sodium current in the adult human heart

Arrhythmogenic and antiarrhythmic actions of late sustained sodium current in the adult human heart

Abstract Late sodium current (late INa) inhibition has been proposed to suppress the incidence of arrhythmias generated by pathological states or induced by drugs. However, the role of late INa in the human heart is still poorly understood. We therefore investigated the role of this conductance in a...

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Bibliographic Details
Main Authors: Anh Tuan Ton, William Nguyen, Katrina Sweat, Yannick Miron, Eduardo Hernandez, Tiara Wong, Valentyna Geft, Andrew Macias, Ana Espinoza, Ky Truong, Lana Rasoul, Alexa Stafford, Tamara Cotta, Christina Mai, Tim Indersmitten, Guy Page, Paul E. Miller, Andre Ghetti, Najah Abi-Gerges
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91528-1

Internet

https://doi.org/10.1038/s41598-021-91528-1

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