Yeast lysates carrying the nucleoprotein from measles virus vaccine as a novel subunit vaccine platform to deliver Plasmodium circumsporozoite antigen

Yeast lysates carrying the nucleoprotein from measles virus vaccine as a novel subunit vaccine platform to deliver Plasmodium circumsporozoite antigen

Abstract Background Yeast cells represent an established bioreactor to produce recombinant proteins for subunit vaccine development. In addition, delivery of vaccine antigens directly within heat-inactivated yeast cells is attractive due to the adjuvancy provided by the yeast cell. In this study, Pi...

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Bibliographic Details
Main Authors: Daria Jacob, Claude Ruffie, Chantal Combredet, Pauline Formaglio, Rogerio Amino, Robert Ménard, Frédéric Tangy, Monica Sala
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Malaria Journal
Subjects:
Plasmodium berghei
Malaria vaccine
CS antigen
Pichia pastoris
Yeast lysate
Measles virus
Online Access:http://link.springer.com/article/10.1186/s12936-017-1908-7

Internet

http://link.springer.com/article/10.1186/s12936-017-1908-7

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