Rapamycin Expands and Confers Resistance to Apoptosis of Human Inducible Regulatory T Cells (TRI)
The immunosuppressive drug Rapamycin (RAPA) has been shown to promote expansion of CD4 + IL-10 + natural human regulatory T cells (nTreg) in vitro and in vivo . RAPA effects on inducible Treg (Tri) are unknown, and this study explores in vitro responses of Tr1 to this drug. CD4 + CD25 neg T cells is...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2013-05-01
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Series: | European Journal of Inflammation |
Online Access: | https://doi.org/10.1177/1721727X1301100214 |