Rapamycin Expands and Confers Resistance to Apoptosis of Human Inducible Regulatory T Cells (TRI)

The immunosuppressive drug Rapamycin (RAPA) has been shown to promote expansion of CD4 + IL-10 + natural human regulatory T cells (nTreg) in vitro and in vivo . RAPA effects on inducible Treg (Tri) are unknown, and this study explores in vitro responses of Tr1 to this drug. CD4 + CD25 neg T cells is...

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Bibliographic Details
Main Authors: C. Bergmann, C.A. Wild, T.K. Hoffmann, S. Lang, T.L. Whiteside
Format: Article
Language:English
Published: SAGE Publishing 2013-05-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X1301100214