Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells

Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells

Neural rosettes (NPC rosettes) are radially arranged groups of cells surrounding a central lumen that arise stochastically in monolayer cultures of human pluripotent stem cell (hPSC)-derived neural progenitor cells (NPC). Since NPC rosette formation is thought to mimic cell behavior in the early neu...

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Bibliographic Details
Main Authors: Ryan F. Townshend, Yue Shao, Sicong Wang, Chari L. Cortez, Sajedeh Nasr Esfahani, Jason R. Spence, K. Sue O’Shea, Jianping Fu, Deborah L. Gumucio, Kenichiro Taniguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
neural rosette
human pluripotent stem cells
cell spreading
neural progenitor cells
actin cytoskeletal network
RhoA
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.588941/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.588941/full

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