Mechanisms of Imidacloprid-Induced Alteration of Hypothalamic-Pituitary-Adrenal (HPA) Axis after Subchronic Exposure in Male Rats

Mechanisms of Imidacloprid-Induced Alteration of Hypothalamic-Pituitary-Adrenal (HPA) Axis after Subchronic Exposure in Male Rats

Imidacloprid (IMI) is known to target the nicotinic acetylcholine receptors (nAChRs) in insects, and potentially in mammals. However, IMI toxicity on mammalian tissues has not been adequately evaluated. The aim of the present study was to examine whether IMI induced functional impairment in hypthala...

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Bibliographic Details
Main Authors: Alya Annabi, Ines El-Bini Dhouib, Houssem Dkhili, Yassine Bdiri, Ines Rejeb, Najoua Gharbi, Saloua El-Fazâa, Mohamed Montassar Lasram
Format: Article
Language:English
Published: HATASO 2015-11-01
Series:Recent Advances in Biology and Medicine
Subjects:
Imidacloprid
HPA axis
Oxidative stress
Cholinergic transmission
Rat
Online Access:https://submissions.scholasticahq.com/reader/rabm/323-mechanisms-of-imidacloprid-induced-alteration-of-hypothalamic-pituitary-adrenal-hpa-axis-after-subchronic-exposure-in-male-rats

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