Modulating p56Lck in T-Cells by a Chimeric Peptide Comprising Two Functionally Different Motifs of Tip from Herpesvirus saimiri

The Lck interacting protein Tip of Herpesvirus saimiri is responsible for T-cell transformation both in vitro and in vivo. Here we designed the chimeric peptide hTip-CSKH, comprising the Lck specific interacting motif CSKH of Tip and its hydrophobic transmembrane sequence (hTip), the latter as a vec...

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Bibliographic Details
Main Authors: Jean-Paul Vernot, Ana María Perdomo-Arciniegas, Luis Alberto Pérez-Quintero, Diego Fernando Martínez
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2015/395371