Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions

Postnatal development of skeletal muscle is a highly dynamic period of tissue remodeling. Here, we used RNA-seq to identify transcriptome changes from late embryonic to adult mouse muscle and demonstrate that alternative splicing developmental transitions impact muscle physiology. The first 2 weeks...

Full description

Bibliographic Details
Main Authors: Amy E Brinegar, Zheng Xia, James Anthony Loehr, Wei Li, George Gerald Rodney, Thomas A Cooper
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/27192