Exosomes as renal inductive signals in health and disease, and their application as diagnostic markers and therapeutic agents

Cells secrete around 30-1000 nm membrane-enclosed vesicles, of which members of the subgroup between 30-100 nm are termed exosomes (EXs). EXs are released into the extracellular space and are widely present in body fluids and incorporated mRNA, miRNA, proteins and signaling molecules. Increasing am...

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Bibliographic Details
Main Authors: Mirja eKrause, Anatoliy eSamoylenko, Seppo J Vainio
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00065/full