Idebenone Protects against Acute Murine Colitis via Antioxidant and Anti-Inflammatory Mechanisms

Idebenone Protects against Acute Murine Colitis via Antioxidant and Anti-Inflammatory Mechanisms

Oxidative stress is a key player of the inflammatory cascade responsible for the initiation of ulcerative colitis (UC). Although the short chain quinone idebenone is considered a potent antioxidant and a mitochondrial electron donor, emerging evidence suggests that idebenone also displays anti-infla...

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Bibliographic Details
Main Authors: Sonia Shastri, Tanvi Shinde, Sukhwinder Singh Sohal, Nuri Gueven, Rajaraman Eri
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
idebenone
cytokines
inflammatory bowel disease
lipid peroxidation
superoxide dismutase
tight junction proteins and ulcerative colitis
Online Access:https://www.mdpi.com/1422-0067/21/2/484

Internet

https://www.mdpi.com/1422-0067/21/2/484

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