Idebenone Protects against Acute Murine Colitis via Antioxidant and Anti-Inflammatory Mechanisms
Oxidative stress is a key player of the inflammatory cascade responsible for the initiation of ulcerative colitis (UC). Although the short chain quinone idebenone is considered a potent antioxidant and a mitochondrial electron donor, emerging evidence suggests that idebenone also displays anti-infla...
Main Authors: | Sonia Shastri, Tanvi Shinde, Sukhwinder Singh Sohal, Nuri Gueven, Rajaraman Eri |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-01-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/2/484 |
Similar Items
-
Idebenone Protects against Spontaneous Chronic Murine Colitis by Alleviating Endoplasmic Reticulum Stress and Inflammatory Response
by: Sonia Shastri, et al.
Published: (2020-09-01) -
Short-Chain Naphthoquinone Protects Against Both Acute and Spontaneous Chronic Murine Colitis by Alleviating Inflammatory Responses
by: Sonia Shastri, et al.
Published: (2021-08-01) -
Idebenone: When an antioxidant is not an antioxidant
by: Nuri Gueven, et al.
Published: (2021-01-01) -
Role of oxidative stress & antioxidant defence in ulcerative colitis patients from north India
by: S. V. Rana, et al.
Published: (2014-01-01) -
Border between natural product and drug: Comparison of the related benzoquinones idebenone and coenzyme Q10
by: Nuri Gueven, et al.
Published: (2015-04-01)