The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis

The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis

Abstract The tissue diagnosis of amyloidosis and confirmation of fibril protein type, which are crucial for clinical management, have traditionally relied on Congo red (CR) staining followed by immunohistochemistry (IHC) using fibril protein specific antibodies. However, amyloid IHC is qualitative,...

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Bibliographic Details
Main Authors: Tamer Rezk, Janet A Gilbertson, P Patrizia Mangione, Dorota Rowczenio, Nigel B Rendell, Diana Canetti, Helen J Lachmann, Ashutosh D Wechalekar, Paul Bass, Philip N Hawkins, Vittorio Bellotti, Graham W Taylor, Julian D Gillmore
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:The Journal of Pathology: Clinical Research
Subjects:
amyloid
mass spectrometry
proteomics
immunohistochemistry
Online Access:https://doi.org/10.1002/cjp2.126

Internet

https://doi.org/10.1002/cjp2.126

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