SpatialDWLS: accurate deconvolution of spatial transcriptomic data

Abstract Recent development of spatial transcriptomic technologies has made it possible to characterize cellular heterogeneity with spatial information. However, the technology often does not have sufficient resolution to distinguish neighboring cell types. Here, we present spatialDWLS, to quantitat...

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Bibliographic Details
Main Authors: Rui Dong, Guo-Cheng Yuan
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02362-7