Atypical chromosome abnormalities in acute myeloid leukemia type M4

This study reports an adult AML-M4 patient with atypical chromosomal aberrations present in all dividing bone marrow cell at diagnosis: t(1;8)(p32.1;q24.2), der(9)t(9;10)(q22;?), and ins(19;9)(p13.3;q22q34) that may have originated transcripts with leukemogenic potential.

Bibliographic Details
Main Authors: Agnes C. Fett-Conte, Roseli Viscardi Estrela, Cristina B. Vendrame-Goloni, Andréa B. Carvalho-Salles, Octávio Ricci-Júnior, Marileila Varella-Garcia
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2007-01-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000100002