Upregulation of miR-941 in Circulating CD14+ Monocytes Enhances Osteoclast Activation via WNT16 Inhibition in Patients with Psoriatic Arthritis

Upregulation of miR-941 in Circulating CD14+ Monocytes Enhances Osteoclast Activation via WNT16 Inhibition in Patients with Psoriatic Arthritis

Psoriatic arthritis (PsA) is a destructive joint disease mediated by osteoclasts. MicroRNAs (miRNAs) regulate several important pathways in osteoclastogenesis. We profiled the expression of miRNAs in CD14+ monocytes from PsA patients and investigated how candidate microRNAs regulate the pathophysiol...

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Bibliographic Details
Main Authors: Shang-Hung Lin, Ji-Chen Ho, Sung-Chou Li, Yu-Wen Cheng, Yi-Chien Yang, Jia-Feng Chen, Chung-Yuan Hsu, Toshiaki Nakano, Feng-Sheng Wang, Ming-Yu Yang, Chih-Hung Lee, Chang-Chun Hsiao
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
psoriatic arthritis
osteoclastogenesis
miR-941
WNT16
Online Access:https://www.mdpi.com/1422-0067/21/12/4301

Internet

https://www.mdpi.com/1422-0067/21/12/4301

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