HIV-1 capture and transmission by dendritic cells: the role of viral glycolipids and the cellular receptor Siglec-1.
Dendritic cells (DCs) are essential in order to combat invading viruses and trigger antiviral responses. Paradoxically, in the case of HIV-1, DCs might contribute to viral pathogenesis through trans-infection, a mechanism that promotes viral capture and transmission to target cells, especially after...
Main Authors: | Nuria Izquierdo-Useros, Maier Lorizate, Paul J McLaren, Amalio Telenti, Hans-Georg Kräusslich, Javier Martinez-Picado |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-07-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4102576?pdf=render |
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