Interaction of the Host and Viral Genome and Their Influence on HIV Disease

by Riley H. Tough, Riley H. Tough, Paul J. McLaren, Paul J. McLaren
Published 2019-01-01

Retroviruses As Myeloid Cell Riders: What Natural Human Siglec-1 “Knockouts” Tell Us About Pathogenesis

by Javier Martinez-Picado, Javier Martinez-Picado, Javier Martinez-Picado, Paul J. McLaren, Paul J. McLaren, Amalio Telenti, Nuria Izquierdo-Useros
Published 2017-11-01

Estimating the Respective Contributions of Human and Viral Genetic Variation to HIV Control.

by István Bartha, Paul J McLaren, Chanson Brumme, Richard Harrigan, Amalio Telenti, Jacques Fellay
Published 2017-02-01

Analysis of stop-gain and frameshift variants in human innate immunity genes.

by Antonio Rausell, Pejman Mohammadi, Paul J McLaren, Istvan Bartha, Ioannis Xenarios, Jacques Fellay, Amalio Telenti
Published 2014-07-01

HIV-1 capture and transmission by dendritic cells: the role of viral glycolipids and the cellular receptor Siglec-1.

by Nuria Izquierdo-Useros, Maier Lorizate, Paul J McLaren, Amalio Telenti, Hans-Georg Kräusslich, Javier Martinez-Picado
Published 2014-07-01

The Characteristics of Heterozygous Protein Truncating Variants in the Human Genome.

by István Bartha, Antonio Rausell, Paul J McLaren, Pejman Mohammadi, Manuel Tardaguila, Nimisha Chaturvedi, Jacques Fellay, Amalio Telenti
Published 2015-12-01

A novel Acute Retroviral Syndrome Severity Score predicts the key surrogate markers for HIV-1 disease progression.

by Dominique L Braun, Roger Kouyos, Corinna Oberle, Christina Grube, Beda Joos, Jacques Fellay, Paul J McLaren, Herbert Kuster, Huldrych F Günthard
Published 2014-01-01

Disentangling human tolerance and resistance against HIV.

by Roland R Regoes, Paul J McLaren, Manuel Battegay, Enos Bernasconi, Alexandra Calmy, Huldrych F Günthard, Matthias Hoffmann, Andri Rauch, Amalio Telenti, Jacques Fellay, Swiss HIV Cohort Study
Published 2014-09-01

The influence of human genetic variation on Epstein–Barr virus sequence diversity

by Sina Rüeger, Christian Hammer, Alexis Loetscher, Paul J. McLaren, Dylan Lawless, Olivier Naret, Daniel P. Depledge, Sofia Morfopoulou, Judith Breuer, Evgeny Zdobnov, Jacques Fellay, the Swiss HIV Cohort Study
Published 2021-02-01

Identification of Siglec-1 null individuals infected with HIV-1

by Javier Martinez-Picado, Paul J. McLaren, Itziar Erkizia, Maureen P. Martin, Susana Benet, Margalida Rotger, Judith Dalmau, Dan Ouchi, Steven M. Wolinsky, Sudhir Penugonda, Huldrych F. Günthard, Jacques Fellay, Mary Carrington, Nuria Izquierdo-Useros, Amalio Telenti
Published 2016-08-01

Author Correction: The influence of human genetic variation on Epstein–Barr virus sequence diversity

by Sina Rüeger, Christian Hammer, Alexis Loetscher, Paul J. McLaren, Dylan Lawless, Olivier Naret, Nina Khanna, Enos Bernasconi, Matthias Cavassini, Huldrych F. Günthard, Christian R. Kahlert, Andri Rauch, Daniel P. Depledge, Sofia Morfopoulou, Judith Breuer, Evgeny Zdobnov, Jacques Fellay, the Swiss HIV Cohort Study
Published 2021-04-01

Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles

by Susana Benet, Cristina Gálvez, Francis Drobniewski, Irina Kontsevaya, Lilibeth Arias, Marta Monguió‐Tortajada, Itziar Erkizia, Victor Urrea, Ruo‐Yan Ong, Marina Luquin, Maeva Dupont, Jakub Chojnacki, Judith Dalmau, Paula Cardona, Olivier Neyrolles, Geanncarlo Lugo‐Villarino, Christel Vérollet, Esther Julián, Hansjakob Furrer, Huldrych F. Günthard, Paul R. Crocker, Gustavo Tapia, Francesc E. Borràs, Jacques Fellay, Paul J. McLaren, Amalio Telenti, Pere‐Joan Cardona, Bonaventura Clotet, Cristina Vilaplana, Javier Martinez‐Picado, Nuria Izquierdo‐Useros
Published 2021-01-01

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

by István Bartha, Jonathan M Carlson, Chanson J Brumme, Paul J McLaren, Zabrina L Brumme, Mina John, David W Haas, Javier Martinez-Picado, Judith Dalmau, Cecilio López-Galíndez, Concepción Casado, Andri Rauch, Huldrych F Günthard, Enos Bernasconi, Pietro Vernazza, Thomas Klimkait, Sabine Yerly, Stephen J O’Brien, Jennifer Listgarten, Nico Pfeifer, Christoph Lippert, Nicolo Fusi, Zoltán Kutalik, Todd M Allen, Viktor Müller, P Richard Harrigan, David Heckerman, Amalio Telenti, Jacques Fellay, for the HIV Genome-to-Genome Study and the Swiss HIV Cohort Study
Published 2013-10-01

GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers.

by Shengping Li, Ji Qian, Yuan Yang, Wanting Zhao, Juncheng Dai, Jin-Xin Bei, Jia Nee Foo, Paul J McLaren, Zhiqiang Li, Jingmin Yang, Feng Shen, Li Liu, Jiamei Yang, Shuhong Li, Shandong Pan, Yi Wang, Wenjin Li, Xiangjun Zhai, Boping Zhou, Lehua Shi, Xinchun Chen, Minjie Chu, Yiqun Yan, Jun Wang, Shuqun Cheng, Jiawei Shen, Weihua Jia, Jibin Liu, Jiahe Yang, Zujia Wen, Aijun Li, Ying Zhang, Guoliang Zhang, Xianrong Luo, Hongbo Qin, Minshan Chen, Hua Wang, Li Jin, Dongxin Lin, Hongbing Shen, Lin He, Paul I W de Bakker, Hongyang Wang, Yi-Xin Zeng, Mengchao Wu, Zhibin Hu, Yongyong Shi, Jianjun Liu, Weiping Zhou
Published 2012-01-01

Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls.

by Paul J McLaren, Cédric Coulonges, Stephan Ripke, Leonard van den Berg, Susan Buchbinder, Mary Carrington, Andrea Cossarizza, Judith Dalmau, Steven G Deeks, Olivier Delaneau, Andrea De Luca, James J Goedert, David Haas, Joshua T Herbeck, Sekar Kathiresan, Gregory D Kirk, Olivier Lambotte, Ma Luo, Simon Mallal, Daniëlle van Manen, Javier Martinez-Picado, Laurence Meyer, José M Miro, James I Mullins, Niels Obel, Stephen J O'Brien, Florencia Pereyra, Francis A Plummer, Guido Poli, Ying Qi, Pierre Rucart, Manj S Sandhu, Patrick R Shea, Hanneke Schuitemaker, Ioannis Theodorou, Fredrik Vannberg, Jan Veldink, Bruce D Walker, Amy Weintrob, Cheryl A Winkler, Steven Wolinsky, Amalio Telenti, David B Goldstein, Paul I W de Bakker, Jean-François Zagury, Jacques Fellay
Published 2013-01-01