Micro/nano-textured hierarchical titanium topography promotes exosome biogenesis and secretion to improve osseointegration

Abstract Background Micro/nano-textured hierarchical titanium topography is more bioactive and biomimetic than smooth, micro-textured or nano-textured titanium topographies. Bone marrow mesenchymal stem cells (BMSCs) and exosomes derived from BMSCs play important roles in the osseointegration of tit...

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Bibliographic Details
Main Authors: Zhengchuan Zhang, Ruogu Xu, Yang Yang, Chaoan Liang, Xiaolin Yu, Yun Liu, Tianlu Wang, Yi Yu, Feilong Deng
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-021-00826-3