Organocatalytic asymmetric Henry reaction of 1H-pyrrole-2,3-diones with bifunctional amine-thiourea catalysts bearing multiple hydrogen-bond donors

Organocatalytic asymmetric Henry reaction of 1H-pyrrole-2,3-diones with bifunctional amine-thiourea catalysts bearing multiple hydrogen-bond donors

For the first time, a catalytic asymmetric Henry reaction of 1H-pyrrole-2,3-diones was achieved with a chiral bifunctional amine-thiourea as a catalyst possessing multiple hydrogen-bond donors. With this developed method, a range of 3-hydroxy-3-nitromethyl-1H-pyrrol-2(3H)-ones bearing quaternary ste...

Full description

Bibliographic Details
Main Authors: Ming-Liang Zhang, Deng-Feng Yue, Zhen-Hua Wang, Yuan Luo, Xiao-Ying Xu, Xiao-Mei Zhang, Wei-Cheng Yuan
Format: Article
Language:English
Published: Beilstein-Institut 2016-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
asymmetric catalysis
bifunctional catalysts
Henry reaction
organocatalysis
1H-pyrrole-2,3-diones
Online Access:https://doi.org/10.3762/bjoc.12.31

Internet

https://doi.org/10.3762/bjoc.12.31

Similar Items